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Since selenium supplementation in the forms of sodium selenite and SeM was well documented to induce the expressions of seleno-GPxs through their metabolic assimilation into bioavailable selenium (hydrogen selenide), the initial studies focused on exploring selenium supplementation as a strategy to achieve protection against radiation-induced toxicity [38, 66]

There, they help filter blue light and act as antioxidants, protecting retinal tissues from oxidative stress and light-induced damage

108,109 These findings provide a prime collateral lethality therapeutic strategy for the treatment of a substantial fraction of GC or PDAC patients

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